Saquinavir
- Saquinavir
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Saquinavir |
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Structure chimique du saquinavir |
Général |
Nom IUPAC |
(2S)-N-[(2S,3R)-4-[(3S)-3-(tert-butylcarbamoyl)-décahydroisoquinoléin-2-yl]-3-hydroxy-1-phénylbutan-2-yl]-2-(quinoléin-2-ylformamido)butanediamide |
No CAS |
127779-20-8 |
Code ATC |
AE01 |
SMILES |
C1[ N@@]([ C@@ H]( C[ C@@ H] 2CCCC[ C@@ H] 12) C( NC( C)( C) C)= O) C[ C@ H]([ C@ H]( Cc1ccccc1) NC([ C@@ H]( NC( c1nc2c( cccc2) cc1)= O) CC( N)= O)= O) O
PubChem, Vue 3D
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InChI |
InChI : Vue 3D
InChI= 1/ C38H50N6O5/ c1- 38( 2, 3) 43- 37( 49) 32- 20- 26- 14- 7- 8- 15- 27( 26) 22- 44( 32) 23- 33( 45) 30( 19- 24- 11- 5- 4- 6- 12- 24) 41- 36( 48) 31( 21- 34( 39) 46) 42- 35( 47) 29- 18- 17- 25- 13- 9- 10- 16- 28( 25) 40- 29/ h4- 6, 9- 13, 16- 18, 26- 27, 30- 33, 45H, 7- 8, 14- 15, 19- 23H2, 1- 3H3,( H2, 39, 46)( H, 41, 48)( H, 42, 47)( H, 43, 49)/ t26?, 27?, 30-, 31-, 32-, 33+/ m0/ s1
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Propriétés chimiques |
Formule brute |
C38H50N6O5 [Isomères]
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Masse molaire[1] |
670,8408 ± 0,0366 g·mol-1
C 68,04 %, H 7,51 %, N 12,53 %, O 11,92 %,
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Unités du SI & CNTP, sauf indication contraire.
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Notes et références
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Saquinavir — Systematic (IUPAC) name (2S) N [(2S,3R) 4 [(3S) 3 (tert butylcarbamoyl) decahydroisoquinolin 2 yl] 3 hydroxy 1 phenylbutan 2 yl] 2 (quinolin 2 ylformamido)butanediamide … Wikipedia
Saquinavir — Saltar a navegación, búsqueda Saquinavir … Wikipedia Español
saquinavir — Antirretroviral inhibidor de la proteasa. Indicaciones: se prescribe en el tratamiento del síndrome de inmunodeficiencia adquirida. Contraindicaciones: el fármano no debe administrarse a pacientes con escasa biodisponibilidad. Efectos adversos:… … Diccionario médico
Saquinavir — Strukturformel Allgemeines Freiname Saquinavir Andere Namen … Deutsch Wikipedia
saquinavir — noun a weak protease inhibitor (trade name Invirase) used in treating HIV • Syn: ↑Invirase • Hypernyms: ↑protease inhibitor, ↑PI * * * saquinavir /sə kwinˈə vir/ noun A protease inhibitor used as a drug in the treatment of HIV … Useful english dictionary
saquinavir mesylate — [USP] the mesylate salt of saquinavir, having the same actions and uses as the base; administered orally … Medical dictionary
saquinavir — noun Etymology: sa (perhaps backward spelling of protease) + quinoline + avir, alteration of ovir (as in acyclovir) Date: 1994 a protease inhibitor C38H50N6O5 that is administered in the form of its methylated sulfonic salt especially in… … New Collegiate Dictionary
saquinavir — sa·quin·a·vir (sə kwĭnʹə vîr) n. A protease inhibiting drug usually used in combination with other drugs to suppress the replication of HIV. [saquin (perhaps alteration of (i)soquin(oline): iso + quinoline) + antiviral.] * * * … Universalium
saquinavir — noun An anti retroviral drug of the protease inhibitor class that is used in to treat HIV infected patients … Wiktionary
saquinavir — sa·quin·a·vir sə kwin ə .vir n a protease inhibitor C38H50N6O5 or its mesylate C38H50N6O5·CH4O3S administered orally often in combination with other antiretroviral drugs to treat HIV infection * * * n. see protease inhibitor * * * sa·quin·a·vir… … Medical dictionary