Triflupromazine
- Triflupromazine
-
| Triflupromazine |
 |
| Général |
| Nom IUPAC |
N,N-dimethyl-3-[2-(trifluoromethyl)- 10H-phenothiazin-10-yl]-propan-1-amine |
| No CAS |
146-54-3 |
| No EINECS |
205-673-6 |
| Code ATC |
N05AA05 |
| DrugBank |
APRD00465 |
| PubChem |
5568 |
| Propriétés chimiques |
| Formule brute |
C18H19F3N2S [Isomères]
|
| Masse molaire[1] |
352,417 ± 0,021 g·mol-1
C 61,35 %, H 5,43 %, F 16,17 %, N 7,95 %, S 9,1 %,
|
| Propriétés physiques |
| Pression de vapeur saturante |
5,42×10-7 mmHg à 25 °C[2] |
| Écotoxicologie |
| DL50 |
(souris, oral, 245 mg·kg-1)[2] |
| Données pharmacocinétiques |
| Métabolisme |
hépatique |
|
Unités du SI & CNTP, sauf indication contraire.
|
La triflupromazine est une phénothiazine utilisée comme antipsychotique et antiémétique.
Notes et références
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Triflupromazine — drugbox IUPAC name = N,N dimethyl 3 [2 (trifluoromethyl) 10H phenothiazin 10 yl] propan 1 amine width = 170 CAS number = 146 54 3 ATC prefix = N05 ATC suffix = AA05 ATC supplemental = PubChem = 5568 DrugBank = APRD00465 C=18 | H=19 | F=3 | N=2 |… … Wikipedia
triflupromazine hydrochloride — An antipsychotic closely related chemically and pharmacologically to chlorpromazine. * * * [USP] the monohydrochloride salt of triflupromazine, having the same actions and uses as the base; administered intramuscularly or intravenously … Medical dictionary
triflupromazine — noun A phenothiazine antipsychotic with a high risk of side effects … Wiktionary
triflupromazine — tri·flu·pro·ma·zine .trī .flü prō mə .zēn, zən n a phenothiazine tranquilizer used in the form of its hydrochloride C18H19F3N2S·HCl esp. in the treatment of psychotic disorders and as an antiemetic see VESPRIN * * * tri·flu·pro·ma·zine… … Medical dictionary
146-54-3 — Triflupromazine Triflupromazine Général Nom IUPAC N,N dimethyl 3 [2 (trifluoromethyl) 10H phenothiazin 10 yl] propan 1 amine … Wikipédia en Français
C18H19F3N2S — Triflupromazine Triflupromazine Général Nom IUPAC N,N dimethyl 3 [2 (trifluoromethyl) 10H phenothiazin 10 yl] propan 1 amine … Wikipédia en Français
Prochlorperazine — Systematic (IUPAC) name 2 chloro 10 [3 (4 methyl 1 piperazinyl)propyl] 10H phenothiazine Clinical data AHFS/ … Wikipedia
Promazine — Systematic (IUPAC) name N,N dimethyl 3 (10H phenothiazin 10 yl) propan 1 amine … Wikipedia
Antipsychotic — Advertisement for Thorazine (chlorpromazine) from the 1950s[1] An antipsychotic (or neuroleptic) is a tranquilizing psychiatric medication primarily used to manage psychosis (including delusions or hallucinations, as well as disordered tho … Wikipedia
Phenothiazine — Phenothiazine … Wikipedia
