Sertaconazole
- Sertaconazole
-
| Sertaconazole |
 |
| Général |
| Nom IUPAC |
(R,S)-1-{2-[(7-chloro-1-benzothiophén-3-yl)méthoxy]-2-(2,4-dichlorophényl)éthyl}-1H-imidazole |
| No CAS |
99592-32-2 |
| Code ATC |
AC14 |
| DrugBank |
APRD00305 |
| PubChem |
65863 |
| SMILES |
|
| InChI |
InChI : Vue 3D
InChI=1/C20H15Cl3N2OS/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22/h1-8,11-12,19H,9-10H2
InChIKey :
JLGKQTAYUIMGRK-UHFFFAOYAP
Std. InChI : Vue 3D
InChI=1S/C20H15Cl3N2OS/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22/h1-8,11-12,19H,9-10H2
Std. InChIKey :
JLGKQTAYUIMGRK-UHFFFAOYSA-N
|
| Propriétés chimiques |
| Formule brute |
C20H15Cl3N2OS [Isomères]
|
| Masse molaire[1] |
437,77 ± 0,029 g·mol-1
C 54,87 %, H 3,45 %, Cl 24,3 %, N 6,4 %, O 3,65 %, S 7,32 %,
|
| Données pharmacocinétiques |
| Biodisponibilité |
négligeable |
| Liaison protéique |
>99% dans le plasma |
|
Unités du SI & CNTP, sauf indication contraire.
|
Le sertaconazole est un antifongique.
Mode d'action
Le sertaconazole inhibe la synthèse de l'ergostérol, molécule constitutive de la membrane fongique.
Spécialités contenant du sertaconazole
Références
Wikimedia Foundation.
2010.
Contenu soumis à la licence CC-BY-SA. Source : Article Sertaconazole de Wikipédia en français (auteurs)
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