Tazobactam
- Tazobactam
-
| Tazobactam |
 |
| Général |
| Nom IUPAC |
acide (2S,3S,5R)-3-méthyl-7-oxo-3-(1H-1,2,3-triazol-1-ylméthyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique-4,4-dioxyde |
| No CAS |
89786-04-9 |
| Code ATC |
J01CG02 |
| DrugBank |
EXPT03012 |
| SMILES |
O=S3(=O)[C@@](C)(Cn1ccnn1)[C@@H](N2C(=O)C[C@H]23)C(=O)O
PubChem, Vue 3D
|
| InChI |
InChI : Vue 3D
InChI=1/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
|
| Propriétés chimiques |
| Formule brute |
C10H12N4O5S [Isomères]
|
| Masse molaire[1] |
300,291 ± 0,016 g·mol-1
C 40 %, H 4,03 %, N 18,66 %, O 26,64 %, S 10,68 %,
|
|
Unités du SI & CNTP, sauf indication contraire.
|
Le tazobactam est une molécule antibiotique.
Mode d'action
Le tazobactam inhibe les bêta lactamases, enzymes sécrétées par les bactéries pour détruire les bêta-lactamines en ouvrant leur cycle beta lactame.
Voir aussi
Références
Wikimedia Foundation.
2010.
Contenu soumis à la licence CC-BY-SA. Source : Article Tazobactam de Wikipédia en français (auteurs)
Regardez d'autres dictionnaires:
Tazobactam — Strukturformel Allgemeines Freiname Tazobactam Andere Namen … Deutsch Wikipedia
Tazobactam — drugbox IUPAC name = (2S,3S,5R) 3 methyl 4,4,7 trioxo 3 (triazol 1 ylmethyl) 4$l^{6} thia 1 azabicyclo [3.2.0] heptane 2 carboxylic acid CAS number = 89786 04 9 ATC prefix = J01 ATC suffix = CG02 ATC supplemental = PubChem = DrugBank = EXPT03012… … Wikipedia
tazobactam sodium — the sodium salt of tazobactam, used in combination with piperacillin sodium to broaden its spectrum of activity against beta lactamase–producing organisms … Medical dictionary
tazobactam — noun A compound that inhibits the action of bacterial beta lactamases, used in antibiotics … Wiktionary
tazobactam — taz·o·bac·tam (taz″o bakґtam) a penicillanic acid sulfone derivative similar to sulbactam that acts as a beta lactamase inhibitor … Medical dictionary
Piperacillin/tazobactam — Drugbox type = combo component1 = Piperacillin class1 = Ureidopenicillin antibiotic component2 = Tazobactam class2 = Beta lactamase inhibitor CAS number = 123683 33 0 ATC prefix = J01 ATC suffix = CR05 PubChem = 153901 DrugBank = pregnancy AU =… … Wikipedia
piperacillin-tazobactam — A drug combination that is used to treat infection in people with cancer. Piperacillin is a synthetic penicillin; tazobactam enhances the effectiveness of piperacillin … English dictionary of cancer terms
Beta-lactamase — Beta lactamases are enzymes (EC number|3.5.2.6) produced by some bacteria and are responsible for their resistance to beta lactam antibiotics like penicillins, cephalosporins, cephamycins, ertapenems and carbapenems. These antibiotics have a… … Wikipedia
Piperacillin — drugbox IUPAC name = (2 S ,5 R ,6 R ) 6 { [(2 R ) 2 [(4 ethyl 2,3 dioxo piperazine 1 carbonyl)amino] 2 phenyl acetyl] amino} 3,3 dimethyl 7 oxo 4 thia 1 azabicyclo [3.2.0] heptane 2 carboxylic acid CAS number = 66258 76 2 ATC prefix = J01 ATC… … Wikipedia
Piperacilina — Saltar a navegación, búsqueda Piperacilina … Wikipedia Español
