Répaglinide
- Répaglinide
-
| Répaglinide |
 |
| Général |
| No CAS |
135062-02-1 |
| Code ATC |
BX02 |
| SMILES |
c1c(c(ccc1)[C@H](CC(C)C)NC(=O)Cc1cc(c(cc1)C(O)=O)OCC)N1CCCCC1
PubChem, Vue 3D
|
| InChI |
InChI : Vue 3D
InChI=1/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
|
| Propriétés chimiques |
| Formule brute |
C27H36N2O4 [Isomères]
|
| Masse molaire[1] |
452,5857 ± 0,0257 g·mol-1
C 71,65 %, H 8,02 %, N 6,19 %, O 14,14 %,
|
|
Unités du SI & CNTP, sauf indication contraire.
|
Le répaglinide est une molécule antidiabétique, de la classe des glinides.
Mode d'action
Le répaglinide a le même mode d'action que les sulfonylurées, il se fixe aux canaux potassiques de cellules beta des îlots de Langerhans d'où une sécrétion d'insuline accrue.
Indication
Diabète de type II
Notes et références
Wikimedia Foundation.
2010.
Contenu soumis à la licence CC-BY-SA. Source : Article Répaglinide de Wikipédia en français (auteurs)
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