Rabéprazole
- Rabéprazole
-
| Rabéprazole |
 |
| Général |
| Nom IUPAC |
(RS)-2-([4-(3-méthoxypropoxy)-3-méthylpyridin-2-yl]méthylsulfinyl)-1H-benzo[d]imidazole |
| No CAS |
117976-89-3 |
| Code ATC |
A02BC04 |
| DrugBank |
APRD01212 |
| PubChem |
5029 |
| Propriétés chimiques |
| Formule brute |
C18H21N3O3S [Isomères]
|
| Masse molaire[1] |
359,443 ± 0,022 g·mol-1
C 60,15 %, H 5,89 %, N 11,69 %, O 13,35 %, S 8,92 %,
|
| Données pharmacocinétiques |
| Biodisponibilité |
52% |
| Métabolisme |
principalement,t non enzymatique,
partiellement hépatique (CYP2C19) |
| Demi-vie d’élim. |
1 à 1H30 |
| Excrétion |
90% rénale |
|
Unités du SI & CNTP, sauf indication contraire.
|
Le rabéprazole est un antisécrétoire gastrique inhibiteur de la pompe à protons, antiulcéreux.
Notes et références
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