Endoperoxide
- Endoperoxide
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Un endoperoxide est une molécule hétérocyclique contenant un résidu peroxyde -O-O- dans son cycle.
Dans la voie de synthèse de la prostaglandine H2, un endoperoxide est synthétisé par cyclo-oxygénases (COX1 et COX2) à partir de l'acide arachidonique (oméga 6). Ils peuvent aussi subir l'action de la prostacycline synthase pour synthétiser la prostacycline, ainsi que celle de la thromboxane synthase pour donner du thromboxane A2.
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endoperoxide — noun Date: 1962 any of various biosynthetic intermediates in the formation of prostaglandins … New Collegiate Dictionary
endoperoxide — noun Any heterocycle containing a peroxide O O residue in the ring; found especially in certain intermediates in prostaglandin biosynthesis … Wiktionary
endoperoxide — A peroxide (–O–O–) group that bridges two atoms that are both parts of a larger molecule. * * * en·do·per·ox·ide pə räk .sīd n any of various biosynthetic intermediates in the formation of prostaglandins * * * en·do·per·ox·ide (en″do… … Medical dictionary
endoperoxide — en·do·peroxide … English syllables
endoperoxide — ˌ noun Etymology: end + peroxide : any of various biosynthetic intermediates in the formation of prostaglandins … Useful english dictionary
endoperoxide-D-isomerase — en·do·per·ox·ide D isom·er·ase (en″do pə rokґsīd i somґə rās) prostaglandin D synthase … Medical dictionary
endoperoxide-E-isomerase — en·do·per·ox·ide E isom·er·ase (en″do pə rokґsīd i somґə rās) prostaglandin E synthase … Medical dictionary
endoperoxide reductase — en·do·per·ox·ide re·duc·tase (en″do pə rokґsīd re dukґtās) an enzyme of the oxidoreductase class that catalyzes the conversion of the intermediate prostaglandin H2 (PGH2) to prostaglandin F2α(PGF2α). See also… … Medical dictionary
prostaglandin-endoperoxide synthase — pros·ta·glan·din en·do·per·ox·ide syn·thase (pros″tə glanґdin en″do pər okґsīd sinґthās) [EC 1.14.99.1] an enzyme of the oxidoreductase class that has both cyclooxygenase and peroxidase activities, which together… … Medical dictionary
PTGS1 — Prostaglandin endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) PDB rendering based on 1diy … Wikipedia
