Pentazocine
- Pentazocine
-
| Pentazocine |
 |
| Général |
| Nom IUPAC |
(1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-en-1-yl)-
10-azatricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol |
| No CAS |
359-83-1 |
| No EINECS |
206-634-6 |
| Code ATC |
N02AD01 |
| DrugBank |
APRD01173 |
| PubChem |
441278 |
| SMILES |
c12[C@@]3([C@@H]([C@H]([N@@](C\C=C(/C)C)CC3)Cc1ccc(c2)O)C)C
PubChem, Vue 3D
|
| InChI |
InChI : Vue 3D
InChI=1/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18-,19-/m1/s1
|
| Propriétés chimiques |
| Formule brute |
C19H27NO [Isomères]
|
| Masse molaire[1] |
285,4238 ± 0,0176 g·mol-1
C 79,95 %, H 9,53 %, N 4,91 %, O 5,61 %,
|
| Propriétés physiques |
| T° fusion |
146,3 °C |
| Précautions |
| Inhalation |
orale |
| Données pharmacocinétiques |
| Biodisponibilité |
~20 % oralement |
| Métabolisme |
hépatique |
| Demi-vie de distrib. |
2 à 3 heures |
| Excrétion |
rénale |
|
Unités du SI & CNTP, sauf indication contraire.
|
La pentazocine est un opioïde.
Notes et références
Wikimedia Foundation.
2010.
Contenu soumis à la licence CC-BY-SA. Source : Article Pentazocine de Wikipédia en français (auteurs)
Regardez d'autres dictionnaires:
pentazocine — ● pentazocine nom féminin Dérivé hémisynthétique de la morphine … Encyclopédie Universelle
pentazocine — ☆ pentazocine [pen΄tə zō′sēn΄, pen΄tə zō′sin ] n. [ PENTA + (A)Z(O) + ocine, suffix for an 8 membered ring < L oc(to), EIGHT + INE3] a pain killing, synthetic drug derived from coal tar: used in place of morphine because it is less addictive … English World dictionary
Pentazocine — Drugbox IUPAC name = (1 S ,9 S ,13 S ) 1,13 dimethyl 10 (3 methylbut 2 en 1 yl) 10 azatricyclo [7.3.1.02,7] trideca 2,4,6 trien 4 ol width = 180 CAS number = 359 83 1 ATC prefix = N02 ATC suffix = AD01 PubChem = 441278 DrugBank = APRD01173 C = 19 … Wikipedia
pentazocine hydrochloride — [USP] the hydrochloride salt of pentazocine, administered orally as an analgesic … Medical dictionary
pentazocine lactate — [USP] the lactate salt of pentazocine, administered intramuscularly, intravenously, or subcutaneously as an analgesic and as an adjunct to anesthesia … Medical dictionary
pentazocine — noun Etymology: probably from penta + az + octa + 2 ine Date: 1963 a synthetic analgesic drug C19H27NO that is less addictive than morphine … New Collegiate Dictionary
pentazocine — /pen taz euh seen /, n. Pharm. a synthetic narcotic analgesic, C19H27NO, used chiefly for the relief of moderate to severe pain. [1960 65; PENTA + (benz)azocine, a component of its chemical name] * * * … Universalium
pentazocine — noun A particular narcotic painkiller of the benzomorphan class of opioids … Wiktionary
pentazocine — An opioid agonist/antagonist analgesic with some addiction liability but only rare withdrawal syndrome and tolerance; very irritating to tissues on local injection; available as the hydrochloride and lactate salts. * * * pen·taz·o·cine pen taz ə … Medical dictionary
pentazocine — pen·taz·o·cine … English syllables
