Phagosome

Phagosome

Le phagosome est un organite formé dans une cellule phagocytaire à la suite de la phagocytose. On a d'abord décrit la formation du phagosome comme étant une invagination de la membrane plasmique pour englober un corps étranger (bactérie ou débris de cellule) suivie de la fusion de cette membrane pour former une vacuole dans le cytosol.

Des études récentes ont montré que pour le macrophage, la source de membrane nécessaire à la formation du phagosome n'est pas exclusivement la membrane plasmique mais aussi la membrane du réticulum endoplasmique. La membrane du phagosome contient donc des protéines originaires de la membrane plasmique, du réticulum endoplasmique en plus des protéines provenant des endosomes et des lysosomes avec lesquels le phagosome fusionne au cours de sa maturation.


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  • phagosome — phagosome. См. фагосома. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Phagosome — In cell biology, a phagosome is a vacuole formed around a particle absorbed by phagocytosis. The vacuole is formed by the fusion of the cell membrane around the particle. A phagosome is a cellular compartment in which pathogenic microorganisms… …   Wikipedia

  • phagosome — n. [Gr. phagein, to eat; soma, body] A membrane bound vesicle in the cytoplasm of a cell resulting from phagocytosis …   Dictionary of invertebrate zoology

  • phagosome — /fag euh sohm /, n. a vacuole within a phagocyte that contains bacteria or other ingested particles and that becomes fused with a lysosome. [1955 60; PHAGO + SOME3] * * * …   Universalium

  • phagosome — noun A membrane bound vacuole within a cell containing foreign material captured by phagocytosis. See Also: phagosomal …   Wiktionary

  • phagosome — A vesicle that forms around a particle (bacterial or other) within the phagocyte that engulfed it, separates from the cell membrane, and then fuses with and receives the contents of cytoplasmic granules (lysosomes), thus forming a phagolysosome… …   Medical dictionary

  • phagosome — phago·some …   English syllables

  • phagosome — phag•o•some [[t]ˈfæg əˌsoʊm[/t]] n. cbl a vacuole that contains the ingested matter of a phagocytic cell • Etymology: 1955–60 …   From formal English to slang

  • phagosome — ˈfagəˌsōm noun ( s) Etymology: phag + some (III) : a membrane bound vesicle that encloses particulate matter taken into the cell by phagocytosis …   Useful english dictionary

  • Phagosome crystal structures — Cells can ingest foreign particles by a process known as phagocytosis. If large numbers of small particles are introduced in this way, they arrange into crystallites.Cell assisted assembly of colloidal crystalliteSpatial confinement drives… …   Wikipedia

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