Hyaluronidase

Hyaluronidase

Les hyaluronidases (EC 3.2.1.35) sont une classe d'enzymes qui dégradent les acides hyaluroniques

En catalysant l'hydrolyse des acides hyaluroniques, des composants majeurs des liaisons inter-cellulaires, les hyaluronidases abaissent la viscosité des acides hyaluroniques et donc augmentent leurs perméabilités.

Exemple de l'activité hyaluronidase : La protéine PH-20 (située sur la membrane plasmique des spermatozoïdes) possède une activité hyaluronidase, ce qui lui permet de dégrader la matrice extra-cellulaire de la Corona Radiata (d'un follicule), riche en acide hyaluronique.


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Regardez d'autres dictionnaires:

  • Hyaluronidase — Bezeichner Gen Name …   Deutsch Wikipedia

  • hyaluronidase — ● hyaluronidase nom féminin Enzyme diminuant la viscosité des milieux riches en acide hyaluronique …   Encyclopédie Universelle

  • hyaluronidase — [hī΄əl o͞orän′i dās΄] n. [< HYALURONIC ACID + ID(E) + ASE] an enzyme that inactivates hyaluronic acid by breaking down its polymeric structure, thus promoting the diffusion of substances through tissues: found in sperm cells, certain venoms… …   English World dictionary

  • Hyaluronidase — drugbox IUPAC name = Sheep hyaluronidase CAS number = 488712 31 8 ATC prefix = B06 ATC suffix = AA03 ATC supplemental = PubChem = DrugBank = BTD00022 C=2455 | H=3775 | N=617 | O=704 | S=21 molecular weight = 53870.9 g/mol bioavailability =… …   Wikipedia

  • hyaluronidase — 1. Term used loosely for hyaluronate lyase, hyaluronoglucosaminidase, and hyaluronoglucuronidase, one or more of which are present in testis, sperm, other organs, bee and snake venoms, type II pneumonococci, certain hemolytic …   Medical dictionary

  • hyaluronidase — n. an enzyme that depolymerizes hyaluronic acid and therefore increases the permeability of connective tissue. Hyaluronidase is found in the testes, in semen, and in other tissues …   The new mediacal dictionary

  • Hyaluronidase deficiency — (also known as Mucopolysaccharidosis type IX ) is a condition caused by mutations in HYAL1, and characterized by multiple soft tissue masses.[1]:544 See also Morquio syndrome Hunter syndrome Hurler syndrome Skin lesion References …   Wikipedia

  • hyaluronidase — noun Etymology: International Scientific Vocabulary, from hyaluronic (acid) + idase (as in glucosidase) Date: 1940 a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid …   New Collegiate Dictionary

  • hyaluronidase — Enzyme that degrades hyaluronic acid; found in lysosomes …   Dictionary of molecular biology

  • hyaluronidase — /huy euh loo ron i days , dayz /, n. 1. Biochem. a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down… …   Universalium

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