L'hypothèse du cyclol est le premier modèle structurel (en) du repliement des protéines globulaires.
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Cyclol — Figure 1: In the classic cyclol reaction, two peptide groups are linked by a N C’ bond, converting the carbonyl oxygen into a hydroxyl group. Although this reaction occurs in a few cyclic peptides, it is disfavored by free energy, mainly because… … Wikipedia
cyclol — A cyclic dipeptide postulated as occurring in proteins; it does occur in some of the ergot alkaloids … Medical dictionary
Hipótesis del ciclol — Reacción del ciclol clásica. Dos grupos peptídicos se unen por enlace N C , convirtiendo el oxígeno carbonílico en una grupo hidroxilo. Si bien esta reacción ocurre en unos pocos péptidos cíclicos, es desfavor … Wikipedia Español
Dorothy Maud Wrinch — (12 September 1894 – 11 February 1976; married names Nicholson, Glaser) was a mathematician and biochemical theorist best known for her attempt to deduce protein structure using mathematical principles. Dorothy Wrinch was born in Rosario,… … Wikipedia
History of molecular biology — The history of molecular biology begins in the 1930s with the convergence of various, previously distinct biological disciplines: biochemistry, genetics, microbiology, and virology. With the hope of understanding life at its most fundamental… … Wikipedia
Carl Niemann — Carl George Niemann (July 6, 1908 April 29, 1964) was an American biochemist who worked extensively on the chemistry and structure of proteins, publishing over 260 research papers. He is known, with Max Bergmann, for proposing the Bergmann… … Wikipedia
Primary structure — In biochemistry, the primary structure of a biological molecule is the exact specification of its atomic composition and the chemical bonds connecting those atoms (including stereochemistry). For a typical unbranched, un crosslinked biopolymer… … Wikipedia
Ergoline — Systematic (IUPAC) name (6aR) 4,6,6a,7,8,9,10,10a octahydroindolo [4,3 fg] quinoline Clinical data Preg … Wikipedia
Frederick Charles Frank — Sir Frederick Charles Frank FRS[1] (6 March 1911–5 April 1998) was a British theoretical physicist.[2] He was born in Durban, South Africa, although his parents returned to England soon afterwards. He was educated at Thetford Grammar School and… … Wikipedia
Protein — Proteins are large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid residues. The sequence of amino acids in a protein is defined by … Wikipedia
