Myeloid-derived Suppressor Cells
- Myeloid-derived Suppressor Cells
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Cellule myeloïde suppressive
Les cellules myéloïdes suppressives (Myeloid-derived suppressor cells ou MdSC) sont des cellules immunitaires, d'origine myéloïde, comme les monocytes, mais dont les propriétés sont immunosuppressives.
Chez la souris, leur définition phénotypique est Gr1 (Ly-6G/C)+ et CD11b+. Chez les humains, la définition phénotypique n'est pas encore standardisée. Cependant, les MdSC humaines sont souvent définies comme monocytaires (CD33+) et immatures (HLA-DR-) ou encore comme CD14- et CD11b+.
Voir aussi
- Portail de la médecine
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