Enzyme glucuronosyltransférase

Enzyme glucuronosyltransférase

Glucuronyltransférase

La glucuronyltransférase est une enzyme détoxifiante se situant dans le tissu hépatique. Elle sert principalement à la transformation de la bilirubine non conjuguée (ou libre) en bilirubine conjuguée.

Pathologie

Le déficit en enzyme glucuronyltransférase est responsable de troubles variant selon son importance. Le déficit partiel conduit à la maladie de Gilbert et un déficit total à la maladie de Crigler-Najjar.

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