Métalloprotéinases
- Métalloprotéinases
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Métalloprotéinase matricielle
Les métalloprotéinases matricielles ou MMP (de l'anglais Matrix metalloproteinase) sont des enzymes qui dégradent la matrice extracellulaire des tissus conjonctifs, notamment de la peau.
Il en existe de nombreux types (une trentaine environ) :
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metalloproteinases — metalloproteinases. См. металлопротеиназы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Tissue inhibitor of metalloproteinases — The matrix metalloproteinases are inhibited by specific endogenous tissue inhibitor of metalloproteinases (TIMPs), which comprise a family of four protease inhibitors: TIMP1 , TIMP2 , TIMP3 and TIMP4 . Overall, all MMPs are inhibited by TIMPs… … Wikipedia
tissue inhibitors of metalloproteinases — (= TIMP) Family of proteins of around 200 residues that can inhibit metalloproteinases, for example collagenase, by binding to them … Dictionary of molecular biology
matrix metalloproteinases — Proteolytic enzymes that degrade extracellular matrix. Include collagenases and elastases. Inhibitors are predicted to have benefits in arthritis and metastasis though this remains to be proven … Dictionary of molecular biology
Metalloproteinase — Metalloproteinases (or metalloproteases) constitute a family of enzymes from the group of proteases, classified by the nature of the most prominent functional group in their active site. These are proteolytic enzymes whose catalytic mechanism… … Wikipedia
металлопротеиназы — metalloproteinases (MMPs) металлопротеиназы. Группа протеолитических ферментов, вырабатываемых резидентными и участвующими в воспалительных процессах клетками и (в совокупности) способных разрушать практически все макромолекулы, находящиеся в… … Молекулярная биология и генетика. Толковый словарь.
TIMP3 — TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory), also known as TIMP3, is a human gene. PBB Summary section title = summary text = This gene belongs to the tissue inhibitor of metalloproteinases gene family. The… … Wikipedia
Matrix metalloproteinase — Cell surface associated MT1 MMP (MMP14), Green fluorescent protein (GFP) fused to the C term produces a signal on the surface of the cell[1] Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases; other family members are adamalysins … Wikipedia
MMP3 — Matrix metallopeptidase 3 (stromelysin 1, progelatinase) PDB rendering based on 1b3d … Wikipedia
TIMP4 — TIMP metallopeptidase inhibitor 4, also known as TIMP4, is a human gene.cite web | title = Entrez Gene: TIMP4 TIMP metallopeptidase inhibitor 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7079|… … Wikipedia
